Publisher DOI: 10.1007/s430-001-8025-x
Title: Cecropins, antibacterial peptides from insects and mammals, are potently fungicidal against Candida albicans
Language: English
Authors: Andrä, Jörg 
Berninghausen, Otto 
Leippe, Matthias 
Keywords: Antimicrobial peptides; Candida albicans; Cecropins; Peptide antibiotics
Issue Date: Apr-2001
Publisher: Springer
Journal or Series Name: Medical microbiology and immunology 
Volume: 189
Issue: 3
Startpage: 169
Endpage: 173
Abstract: 
Natural products are the major source of lead compounds for drugs against human pathogens. Among the first natural peptides from animals for which a potent antibacterial activity has been recognized were the cecropins. The 30- to 40-residue α-helical peptides display their activity by permeabilizing the membranes of bacteria. Although originally isolated from insect hemolymph, a structural and fun...
URI: http://hdl.handle.net/20.500.12738/3373
ISSN: 1432-1831
Review status: This version was peer reviewed (peer review)
Institute: Bernhard-Nocht-Institut für Tropenmedizin 
Type: Article
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