Publisher DOI: | 10.1007/s430-001-8025-x |
Title: | Cecropins, antibacterial peptides from insects and mammals, are potently fungicidal against Candida albicans |
Language: | English |
Authors: | Andrä, Jörg Berninghausen, Otto Leippe, Matthias |
Keywords: | Antimicrobial peptides; Candida albicans; Cecropins; Peptide antibiotics |
Issue Date: | Apr-2001 |
Publisher: | Springer |
Journal or Series Name: | Medical microbiology and immunology |
Volume: | 189 |
Issue: | 3 |
Startpage: | 169 |
Endpage: | 173 |
Abstract: | Natural products are the major source of lead compounds for drugs against human pathogens. Among the first natural peptides from animals for which a potent antibacterial activity has been recognized were the cecropins. The 30- to 40-residue α-helical peptides display their activity by permeabilizing the membranes of bacteria. Although originally isolated from insect hemolymph, a structural and fun... |
URI: | http://hdl.handle.net/20.500.12738/3373 |
ISSN: | 1432-1831 |
Review status: | This version was peer reviewed (peer review) |
Institute: | Bernhard-Nocht-Institut für Tropenmedizin |
Type: | Article |
Appears in Collections: | Publications without full text |
Show full item record
Add Files to Item
Note about this record
Export
Items in REPOSIT are protected by copyright, with all rights reserved, unless otherwise indicated.